Patient Education

What to Know Before Your First Ketamine Therapy Session

September 28, 2026The Ketamine Clinic6 min read

Starting a new treatment can bring a mixture of curiosity, hope, and questions. If you are considering ketamine therapy for the first time, knowing what to expect can make the experience feel more comfortable and less uncertain.

At The Ketamine Clinic, patient care begins with a medical and psychiatric evaluation designed to understand your history, goals, and individual needs. Ketamine therapy is not appropriate for everyone, which is why proper screening and clinical supervision are important parts of the process.

Your First Step Is a Consultation

Before treatment begins, patients typically meet with a qualified medical professional to discuss their health history and treatment goals.

During this conversation, you may be asked about:

  • Previous wellness treatments
  • Current medications
  • Medical conditions
  • Previous experiences with ketamine or anesthesia
  • Your treatment goals
  • Any concerns or questions about the process

This evaluation helps your clinical team determine whether ketamine therapy may be an appropriate option for you. You can learn more about what to expect at every step before your visit.

Understanding the Different Treatment Options

Ketamine can be administered through different methods, and the appropriate approach depends on factors such as your clinical needs, medical history, and treatment plan.

The Ketamine Clinic offers several in-clinic treatment options, including:

Your provider can explain the differences between these options and discuss which approach may be suitable for your circumstances.

What Happens During an In-Clinic Session?

During an in-clinic treatment, your care team monitors your clinical response throughout the session.

Ketamine can produce a temporary dissociative or dreamlike experience. People may notice changes in their perception of time, surroundings, thoughts, or sensations.

These experiences can vary from person to person.

Because responses can differ, clinical monitoring is an important part of treatment. Your care team can observe your vital signs and response during the session and provide support throughout the experience.

Creating a Comfortable Environment

The treatment environment can play an important role in helping patients feel comfortable.

A calm setting can give you an opportunity to relax while your clinical team focuses on your safety and well-being.

It is normal to have questions before your first session. You should feel comfortable discussing concerns with your healthcare provider before treatment begins.

What About After Treatment?

Your provider will give you specific instructions for after your session based on your treatment plan.

Because ketamine can temporarily affect perception, coordination, and alertness, patients should follow their provider's instructions regarding transportation, activities, medications, and other precautions following treatment.

Do not make assumptions about what is safe to do after a session. Follow the instructions provided by your medical team. Our new patient information can help you prepare for your visit.

Does Everyone Respond the Same Way?

No.

Every person's medical history, treatment goals, response to medication, and overall circumstances are different.

Some people may experience changes relatively quickly, while others may require additional treatment or a different approach. Ketamine therapy should therefore be viewed as an individualized medical treatment rather than a one-size-fits-all solution.

Your healthcare provider can discuss what may be realistic to expect based on your circumstances.

Questions You May Want to Ask Your Provider

Before beginning treatment, consider asking:

  • Why might ketamine therapy be appropriate for me?
  • Which treatment method are you recommending and why?
  • What should I expect during a session?
  • What side effects or temporary effects should I know about?
  • What should I do before and after treatment?
  • How will my response be monitored?
  • How will we determine whether treatment is helping?
  • Are there other treatment options I should consider?

Having these questions ready can help you have a more productive conversation with your provider.

Your Treatment Should Be Individualized

Ketamine therapy is one component of a broader approach to mental and physical wellness. Depending on the individual's needs, treatment may be combined with other forms of professional care or therapy.

At The Ketamine Clinic, treatment plans are designed around each patient's clinical needs, comfort, and goals.

The clinic provides physician-led ketamine care in Phoenix and serves patients throughout the surrounding Valley communities.

Take the First Step With Questions, Not Pressure

If you are considering ketamine therapy, you do not have to have every answer before your first conversation with a healthcare professional.

A consultation can give you an opportunity to learn more about the treatment, discuss your medical history, ask questions, and determine whether it may be appropriate for you.

Ready to feel like yourself again?

Speak with our team about whether ketamine therapy is right for you. Most patients are seen within days.